NFL Week 16 Picks Roundup

Check out all of our NFL picks and predictions for Week 16.

The Tennessee Titans started Week 16 with an upset win over the San Francisco 49ers on Thursday Night Football. Underdogs will look to follow suit on the rest of another NFL slate impacted by COVID-19 protocols.

Here are our against the spread and Over/Under NFL Week 15 picks (click each link for a full preview).

NFL Week 16 Picks

Saturday, Dec. 25

Cleveland Browns vs. Green Bay Packers | Packers -7.5 | Under 44.5
Browns: SU: 7-7 | ATS: 6-8 | O/U: 7-7
Packers: SU: 11-3 | ATS: 11-3 | O/U: 6-8

Indianapolis Colts vs. Arizona Cardinals | Cardinals -1.5 | Under 50
Colts: SU: 8-6 | ATS: 9-5 | O/U: 8-6
Cardinals: SU: 10-4 | ATS: 9-5 | O/U: 7-7

SEE ALSO: Top Expert Betting Picks for Week 16

Sunday, Dec. 26 (1 p.m. ET)

Detroit Lions vs. Atlanta Falcons | Lions +6.5 | Under 42.5
Lions: SU: 2-11-1 | ATS: 9-5 | O/U: 5-9
Falcons: SU: 6-8 | ATS: 6-8 | O/U: 6-8

Baltimore Ravens vs. Cincinnati Bengals | Ravens +3 | Over 45.5
Ravens: SU: 8-6 | ATS: 7-7 | O/U: 7-7
Bengals: SU: 8-6 | ATS: 7-7 | O/U: 6-8

SEE ALSO: Comeback Player of the Year Picks

Los Angeles Rams vs. Minnesota Vikings | Rams -2.5 | Over 49.5
Rams: SU: 10-4 | ATS: 7-7 | O/U: 7-6-1
Vikings: SU: 7-7 | ATS: 8-6 | O/U: 8-6

Buffalo Bills vs. New England Patriots | Patriots -1.5 | Under 43.5
Bills: SU: 8-6 | ATS: 7-6-1 | O/U: 7-7
Patriots: SU: 9-5 | ATS: 9-5 | O/U: 6-8

Jacksonville Jaguars vs. New York Jets | Jets -2.5 | Over 42
Jaguars: SU: 2-12 | ATS: 4-10 | O/U: 3-11
Jets: SU: 3-11 | ATS: 4-10 | O/U: 8-6

SEE ALSO: Who Will be the Next Head Coach of the Jaguars?

New York Giants vs. Philadelphia Eagles | Eagles -9.5 | Over 40.5
Giants: SU: 4-10 | ATS: 6-8 | O/U: 4-9-1
Eagles: SU: 7-7 | ATS: 7-6-1 | O/U: 8-6

Tampa Bay Buccaneers vs. Carolina Panthers | Panthers +9.5 | Over 43

Buccaneers: SU: 10-4 | ATS: 7-7 | O/U: 7-7
Panthers: SU: 5-9 | ATS: 5-9 | O/U: 7-7

SEE ALSO: Top Expert NFL Prop Picks

Los Angeles Chargers vs. Houston Texans | Chargers -10 | Over 46
Chargers: SU: 8-6 | ATS: 7-7 | O/U: 7-7
Texans: SU: 3-11 | ATS: 6-8 | O/U: 6-8

4 p.m. ET

Chicago Bears vs. Seattle Seahawks | Seahawks -6.5 | Under 44
Bears: SU: 4-10 | ATS: 4-10 | O/U: 5-9
Seahawks: SU: 5-9 | ATS: 7-7 | O/U: 3-11

Pittsburgh Steelers vs. Kansas City Chiefs | Chiefs -7.5 | Under 44
Steelers: SU: 7-6-1 | ATS: 6-8 | O/U: 5-9
Chiefs: SU: 10-4 | ATS: 7-7 | O/U: 7-7

Denver Broncos vs. Las Vegas Raiders | Raiders ML | Under 41.5
Broncos: SU: 7-7 | ATS: 7-7 | O/U: 3-11
Raiders: SU: 7-7 | ATS: 5-9 | O/U: 7-7

Sunday Night Football

Washington Football Team vs. Dallas Cowboys | Cowboys -10.5 | Under 47.5
Washington: SU: 6-8 | ATS: 5-8-1 | O/U: 6-8
Cowboys: SU: 10-4 | ATS: 11-3 | O/U: 6-8

Monday Night Football

Miami Dolphins vs. New Orleans Saints | Dolphins -2.5 | Under 37.5
Dolphins: SU: 7-7 | ATS: 7-6-1 | O/U: 6-8
Saints: SU: 7-7 | ATS: 7-7 | O/U: 6-8

SEE ALSO: All picks and odds. Be sure to check out SportsbookReview.com’s community forums and betting tools.

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