NFL Week 17 opening lines, odds and best bet: Vikings hot heading into NFC North showdown

We have reached the penultimate week of the 2024 NFL regular season. Needless to say, it’s a big one – with playoff implications all over the place. Among the marquee matchups are Chiefs vs. Steelers, Ravens vs. Texans, Packers vs. Vikings, Falcons vs. Commanders and Lions vs. 49ers. 

Make sure you check out our NFL predictions as we add our picks on the side and total for every game throughout the week – and throughout the entire season. Also make sure to check out our NFL best bets page for our top picks. For now, let’s break down the NFL Week 17 opening lines and give our best early bet to make.

NFL Week 17 opening lines and odds 

Odds available at Bet365 Sportsbook at time of publishing 

Kansas City Chiefs -2.5 (-110) vs Pittsburgh Steelers +2.5 (-110) – Wednesday 

Baltimore Ravens -3.5 (-110) vs Houston Texans +3.5 (-110) – Wednesday 

Seattle Seahawks -3.5 (-110) vs Chicago Bears +3.5 (-110) – Thursday Night Football 

Los Angeles Chargers -5.5 (-110) vs New England Patriots +5.5 (-110) – Saturday 

Denver Broncos +3 (-110) vs Cincinnati Bengals -3 (-110) – Saturday 

Arizona Cardinals +5.5 (-105) vs Los Angeles Rams -5.5 (-115)

New York Jets +9.5 (-105) vs Buffalo Bills -9.5 (-110)

Green Bay Packers +1.5 (-110) vs Minnesota Vikings -1.5 (-110) 

Las Vegas Raiders +2.5 (-110) vs New Orleans Saints -2.5 (-110)  

Indianapolis Colts -7.5 (-110) vs New York Giants +7.5 (-110)

Carolina Panthers OFF (OFF) vs Tampa Bay Buccaneers OFF (OFF)

Tennessee Titans +1 (-110) vs Jacksonville Jaguars -1 (-110) 

Miami Dolphins -6 (-110) vs Cleveland Browns +6 (-110) 

Dallas Cowboys OFF (OFF) vs Philadelphia Eagles -OFF (OFF)  

Atlanta Falcons +4.5 (-110) vs Washington Commanders -4.5 (-110) – Sunday Night Football

Detroit Lions -3.5 (-105) vs San Francisco 49ers +3.5 (-115) – Monday Night Football 

Best bet for NFL Week 17: Minnesota Vikings -1.5 over Green Bay Packers (-110)

As a miniscule -1.5 favorite and playing it home, it indicates that Minnesota is rated as being worse than Green Bay – despite a 2.5-game advantage in the standings with a 13-2 record. I’m not seeing it; especially not with the Packers playing on a short week on the heels of a Monday Night Football assignment in Week 16.

The Vikings have won 8 games in a row following Sunday’s 27-24 road victory over Seattle. They also beat the Packers on the road earlier this season via a 31-29 decision back in Week 4. In 5 of the last 6 outings, Sam Darnold has thrown multiple touchdown passes and zero interceptions. I can’t see Green Bay containing both Justin Jefferson and Jordan Addison for 4 quarters, so I have Minnesota winning this one by at least a field goal. 

We’ll have NFL Week 17 picks for every game! 

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