Top Expert Betting Picks for NFL Week 14

Check out our NFL Week 14 expert picks for the best against the spread and Over/Under bets.

Week 14 is the last week of the 2021 NFL season with teams on a bye. We’ll be back to a full 16-game slate in Week 15.

Here’s a look at the top against the spread and Over/Under picks for Week 14 from our team of NFL betting experts (pick confidence based on a 1-to-5-star scale).

Top NFL Week 14 Expert Picks

SEE ALSO: NFL Week 14 Betting Odds, Lines and Picks

Top NFL Week 14 ATS Picks

Panthers -2.5 (-115 via DraftKings)

While the Carolina Panthers lost star running back Christian McCaffrey for the season, they should otherwise be quite healthy out of their bye, and rookie running back Chuba Hubbard filled in well for McCaffrey when he was hurt earlier this season.

Panthers QB Cam Newton had an extra week to learn the offense after being signed off the street. Carolina won 19-13 in Atlanta in Week 8 as Ryan threw for just 146 yards and two picks. Sam Darnold was the Panthers’ starting QB then, and there’s no universe where Newton isn’t better than Darnold. I wouldn’t like this nearly as much at Panthers -3, as I think they may win by a field goal, but Atlanta is 1-4 ATS in its last five games as an underdog. - Jordan

Chiefs -9.5 (-110 via DraftKings)

The Kansas City Chiefs covered this number in four of their last six matchups with the Las Vegas Raiders, including two of the last three games in Kansas City. The Chiefs are a matchup nightmare for the Raiders as K.C.’s elite passing offense puts stress on Vegas’ non-descript secondary. In their Week 10 meeting, Chiefs QB Patrick Mahomes threw five touchdown passes in a 41-14 runaway victory. It was the best showing of the season for the Chiefs’ offense. 

The Chiefs are riding a five-game winning streak that has put them back in contention for the top spot in the AFC. The Raiders are 1-4 ATS in their last five trips to Missouri. - McClymont

49ers -1.5 (-110 via BetMGM)

I loved the San Francisco 49ers even more when they were 1.5-point underdogs, but I'll still take them here considering they are the better team in this matchup.

The 49ers may be coming off a tough road loss against the Seattle Seahawks, but that is a place they normally go to lose football games. They still showcased a great offensive attack and stopped the run as they've done all year long. On the season, San Francisco ranks third in DVOA against the rush, which will make matters real difficult for a Cincinnati Bengals team running it at the 12th-highest rate in the league.

The Bengals' secondary is weak here, too, making the possibility QB Jimmy Garoppolo throws San Francisco out of it very slim. - Ducey

Chargers -10 (-110 via DraftKings)

With QB Jake Fromm set to start his first career game for the New York Giants, there are no excuses on the table for the Los Angeles Chargers. The expectation is to dominate even if several of their stars are banged up.

The Giants will struggle with every aspect of this matchup. The offense couldn't score even with Daniel Jones at the helm, let alone the noodle-armed Fromm. Their defense is poorly matched against the Chargers' pass-happy attack. - Lipka

Top NFL Week 14 O/U Picks

Lions-Broncos Under 42 (-110 via DraftKings)

The forecast is shockingly nice for Sunday in Denver, but the projected total is still set very low. The Detroit Lions went 10 straight games scoring fewer than 20 points before putting up 29 last week on a Minnesota Vikings defense missing several starters.

The Denver Broncos defense is much better than Minnesota’s, and Detroit will likely be without its best all-around offensive player once again in running back D’Andre Swift. The Broncos were held to nine points on Sunday by the Chiefs.

The total has gone Under in five straight Lions road games with an average combined score of 35.2 points. It has gone Under in four of Denver’s last five games as a home favorite with an average combined score of 34.4 points. - Jordan

Raiders-Chiefs Over 47.5 (-105 via Circa)

I’m sticking with the same game, which has the fourth-highest total of the week. The last three meetings between these AFC West rivals finished with totals of 72, 66, and 55 points. The trend says as much about the offenses as it does their defenses. Both the Chiefs and Raiders rank in the bottom half in the league in total defense. Vegas gives up 355.3 yards per game (19th) and K.C. allows 367.7 yards per game (25th). 

Though the game is being played in Kansas City in December, weather isn’t expected to play a factor, as the forecast calls for sunny skies and 11 degrees. It will be perfect conditions for Mahomes and Derek Carr to again bomb away at their opposing defenses. - McClymont

Falcons-Panthers Under 41.5 (-110 via PointsBet)

I will ask you one question here: How will either team score? Sure, the Falcons defense has been a disaster, but so has the Panthers' offense with Newton at the helm. The former MVP has reminded us why he was out of the league for the start of the year with some poor throwing, which has caused head coach Matt Rhule and his staff to resort to running the ball.

Without Christian McCaffery, this isn't going to net a boatload of points, and it's also going to slow the pace of this game down considerably. On the other side, the Panthers defense has actually been quite good against the pass, and there's going to be no issues stopping the non-existent rushing attack of Atlanta. - Ducey

Seahawks-Texans Under 41 (-110 via DraftKings)

Seattle showed good signs of life in its surprising beatdown of San Francisco last week, and that's bad news for the Houston Texans. The Texans are objectively terrible still, offering next to nothing positive most weeks they play. With Seattle playing better with QB Russell Wilson healthy, this will be a big win for the Seahawks.

The best play is the Under. Seattle hit the Under in nine of its last 10 games, whereas Houston has accomplished this in six of seven. Neither offense is terribly explosive, and the Texans in particular will struggle to run the ball. - Lipka

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